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Detecting Microplastics in Human Placenta tissue with Pyrolysis-GC-MS

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Global production of plastic has resulted in the massive release of nano- and micro-plastics. Microplastics have found their way into humans, and scientists are developing a new methods to detect them. In one study, scientists found microplastics present in all 62 placentas tested from people who had recently given birth. They found various types of plastics, including polyethylene, PVC, and nylon.

The team’s methodology included saponification and ultracentrifugation to extract solid material from human placental tissue samples. They used highly specific and quantitative analysis of plastic with pyrolysis-gas chromatography and mass spectroscopy (Py-GC-MS). Placenta tissues were analyzed with fluorescence microscopy and automated particle count, which showed presence of micro-sized particles but not nano sized particles. Compared to other methodologies and tools, PY-GC-MS detected microplastics in all placenta samples.

The data that Py-GC-MS shows advancements in unbiased quantitative resolution and its application to detect microplastics in human placenta tissue samples. This method, with clinical data, could be essential to understanding the potential impacts of microplastics on pregnancy outcomes.

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