Micro- and Nanoplastics Breach the Blood–Brain Barrier

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Abstract: “Humans are continuously exposed to plastics such as in textiles, car tires and packaging. Unfortunately, plastics pollute the environment, causing widespread contamination of micro- and nanoplastics (MNPs). The blood–brain barrier (BBB) is an important biological barrier that protects the brains of living organisms from harmful substances. In this study scientists performed short-term uptake research in mice with orally administered polystyrene (PS) plastic micro-/nanoparticles (9.55 µm, 1.14 µm, 0.293 µm). The research shows that nanometer sized particles—but not bigger particles—reach the brain within only 2 hours after ingestion. Researchers further explain causes of the passive transport of nano-sized plastic particles into the brains of mice.”

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