Prevent and Mitigate the Effects of Endocrine-Disrupting Chemicals

June 10 , 9:30 am June 11 , 5:30 pm EDT

The National Center for Complementary and Integrative Health (NCCIH) is partnering with the National Institute of Environmental Health Sciences (NIEHS) to hold a 2-day workshop to stimulate discussion about and interest in researching ways to reduce and mitigate the effects of endocrine-disrupting chemicals (EDCs) in people who have been exposed. “Complementary and Integrative Interventions To Prevent and Mitigate the Effects of Endocrine-Disrupting Chemicals” will take place June 10–11, 2024. Spanish-language interpretation will be provided for those who indicate the need. 

Register now to join virtually.

  • Members of the public may join by livestream and ask questions in advance of the meeting. 

July 2 , 1:00 pm 2:00 pm EDT

One in six children in the U.S. has a developmental disability and the prevalence of those disabilities has increased over the past decade. Families with low incomes and families of color have long faced disproportionate exposures to toxic chemicals and pollutants known to hinder brain development. These inequities stem from histories of discriminatory policies. 

A recently published literature review, initiated by Project TENDR (Targeting Environmental Neuro-Development Risks), sheds light on the disparities in neurodevelopmental outcomes in children in low-income families and communities of color in the United States. The scoping review, which analyzes more than 200 studies conducted between 1974 and 2022, maps existing literature on seven neurotoxicants, including combustion-related air pollution, lead, mercury, pesticides, phthalates, PBDEs, and PCBs. 

“As a result of discriminatory practices and policies, families with low incomes and families of color are currently and historically disproportionately exposed to chemicals without their knowledge or consent where they live, work, play, pray, and learn,” says co-lead author Dr. Devon Payne-Sturges.

As part of the review process, Project TENDR Health Disparities Workgroup members met with community and environmental justice leaders to identify possible areas of collaboration and opportunities for the research to support the work of the environmental justice organizations.

The review underscores the need for action at all levels of government to limit, lower, and eliminate existing pollutants and toxic chemicals in our environments in order to achieve environmental justice and health equity. It calls for stronger workplace protections and an end to siting chemical and plastics manufacturing facilities in/near communities of color and low-income communities.

In this 1.5 hour discussion hosted by CHE Alaska, Dr. Payne-Sturges and Dr. Tanya Khemet Taiwo, the lead authors of the report, will present their findings and recommendations. Dr. Kristie Ellickson will demonstrate a searchable database of studies on disparities in exposures and impacts. ACAT’s Environmental Health and Justice Director Vi Waghiyi will talk about neurodevelopmental disparities and health inequities specifically in Alaska Native children.

April 18 , 1:00 pm 2:00 pm EDT

In 2022, the UN launched treaty negotiations in Dakar, Senegal, for an internationally legally binding instrument to end plastic pollution. Health was not emphasized in the announcement of the treaty process. Yet the proliferation of plastics has produced large-scale consequences for endocrine diseases and dysfunctions.

Plastics are a source of endocrine-disrupting chemicals, commonly known as EDCs. These EDCs include phthalates (used in food packaging), bisphenols (used in can linings), and per- and polyfluoroalkyl substances, or PFAS (used in non-stick cooking utensils).

Studies across the globe have documented widespread exposure to EDCs used in plastic materials, and their contribution to infertility and non-communicable diseases including obesity, type 2 diabetes, cardiovascular disease, and some cancers.  A recent study documented annual health costs of $250 billion/year related to plastics.

In this webinar, Dr. Leonardo Trasande will discuss research using data from the US National Institutes of Health Environmental influences on Child Health Outcomes (ECHO) Program from 1998 to 2022. The study explored associations of 20 phthalate metabolites with gestational age at birth, birthweight, birth length, and birthweight for gestational age z-scores. The researchers also estimated attributable adverse birth outcomes, and the associated costs. 

This webinar will be moderated by Sharyle Patton, Director of Commonweal’s Biomonitoring Resource Center.

May 7 , 1:00 pm 2:00 pm EDT

Can endocrine disrupting chemicals (EDCs) influence a mother’s hormone levels during pregnancy? In this webinar, Brad Ryva and Dr. Diana Pacyga will discuss their recent study investigating this possibility in pregnant women enrolled in the Illinois Kids Development Study (I-KIDS). This is one of the first studies to investigate mixtures of EDCs and hormone levels during pregnancy. They studied known EDCs, including DEHP and bisphenol A (BPA), as well as chemicals used as replacements, such as DiNCH and bisphenol S (BPS). 

They reported that exposure to certain chemicals during pregnancy was associated with altered maternal hormone levels. In some cases the relationships differed depending on fetal sex. Since hormone levels guide development of the fetus and have effects that can last throughout life, these findings are critically important.

This webinar will be moderated by Sarah Howard of the Healthy Environment and Endocrine Disruptor Strategies (HEEDS) program of Environmental Health Sciences.

March 19 , 1:00 pm 2:00 pm EDT

Despite varied treatment, mitigation, and prevention efforts, the prevalence and severity of obesity continue to rise around the world. In this EDC Strategies Partnership webinar, Dr. Jerry Heindel presents a combined model of obesity causation that links four general models to create a unifying paradigm.

The four models include the energy balance model (EBM), based on calories as the driver of weight gain; the carbohydrate-insulin model (CIM), based on insulin as a driver of energy storage; the oxidation-reduction model (REDOX), based on reactive oxygen species (ROS) as a driver of altered metabolic signaling; and the obesogens model (OBS), which proposes that environmental chemicals interfere with hormonal signaling leading to adiposity.

Dr. Heindel will present a combined OBS/REDOX model in which environmental chemicals present in the air, food, food packaging, and household products generate false autocrine and endocrine metabolic signals. These signals then subvert standard mechanisms of energy regulation, increase basal and stimulated insulin secretion, disrupt energy efficiency, and influence appetite and energy expenditure leading to weight gain.

This combined model incorporates the data supporting the EBM and CIM models, thus creating one integrated model that covers significant aspects of all the mechanisms that are potentially contributing to the obesity pandemic. Importantly, the OBS/REDOX model provides a rationale and approach for future preventative efforts based on environmental chemical exposure reduction.

This webinar will be moderated by Sharyle Patton, Director of Commonweal’s Biomonitoring Resource Center.

October 3, 2023 , 7:00 pm 8:00 pm EDT

Join Beyond Plastics on Tuesday, October 3, 2023 at 7pm ET on Zoom for a conversation about endocrine disruptors with John Peterson ‘Pete’ Myers, Ph.D., CEO and Chief Scientist of Environmental Health Sciences, New York State Senator Pete Harckham, Chair of the New York Senate Environmental Conservation Committee, and Megan Wolff, Ph.D., MPH, Policy Director at Beyond Plastics.